The Single Best Strategy To Use For ceesdekker

The Single Best Strategy To Use For ceesdekker

Blog Article

Applying solitary-molecule optical and AFM imaging and power-spectroscopy tactics, we seek out to unravel the mechanistic elements of the structure and dynamics of chromosomes. Our research passions contain:

Human Rad51 filaments on double- and one-stranded DNA: correlating normal and irregular varieties with recombination perform.

, Groningen scientists existing the outcomes in their efforts to produce labs far more sustainable and supply guidelines for other labs. 

2007, to start with genuine-time detection of strand Trade in homologous recombination by RecA; discovery of a very low persistence length of ends of microtubules; and solved the system of biosensing with carbon nanotubes

2015, discovery that condensin is actually a highly adaptable protein framework; and initial detection of DNA knots using nanopores

The coiled-coil with the human Rad50 DNA mend protein includes specific segments of greater versatility

You're a Christian. If you could potentially make such a synthetic cell, would you be one action nearer to God, or would the part of God have diminished somewhat yet again?

Atomic force microscopy displays that vaccinia topoisomerase IB generates filaments on DNA inside of a cooperative style

2003, shown the primary biosensors manufactured from a carbon nanotube; settled the structure and system of DNA repair service proteins; and discovery of a different procedure for fabricating reliable-state nanopores for DNA translocation

Incredibly awesome, but that wasn’t seriously in which my desire lay. I desired to pioneer And that i experienced the feeling which was not probable, since the most interesting basic insights experienced already been uncovered. But my discipline experienced developed several remarkable new tools to measure particular person molecules. I made a decision that I desired to implement this to biology, to have a look at it from the Actual physical point of view.’

[14] In 2005 Dekker grew to become linked to Netherlands-broad conversations about Intelligent Layout, a movement that he has considering that Plainly distanced himself from. Dekker advocates that science and faith aren't in opposition but might be harmonized.

Cees Dekker is Distinguished University Professor at TU Delft. Trained as being a physicist, he pioneered nanotechnology with numerous discoveries on carbon nanotubes within the 1990s. Because 2000, he moved to single-molecule biophysics and nanobiology. His existing analysis focuses on (i) nanopores for protein sequencing; (ii) chromosome structure, in https://www.ceesdekker.net particular SMC motor protein; and (iii) developing a dwelling synthetic cell from lifeless molecules. Dekker is definitely an elected member of the KNAW and fellow to the APS as well as IOP.

Publisher’s Be aware Springer Nature continues to be neutral with regards to jurisdictional statements in printed maps and institutional affiliations.

Instance (two) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in grey, the rim with the pore is highlighted in red, and also a 3D rendering in the movement from the DNA rod is exhibited.